RFICs
PRODUCTS
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![GettyImages-1327977866-cell-culture-sample-laboratory]( "Development Solutions For Biologics CHO CLD Platforms")
Aragen offers choice of CLD platforms, efficient Upstream and Downstream process development
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![lee company pump]( "Dual Seal Variable Volume Precision Dispense Pump")
The Dual Seal Variable Volume Precision Dispense Pump is a robust, stepper motor-driven positive displacement pump designed for reliable dispensing of complex fluids, including those with high surfactant content or crystallization tendencies.
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This wideband Class AB GaN power amplifier delivers robust RF performance across an expansive frequency range from 50 MHz to 6 GHz, supporting applications that span commercial wireless systems, broadband communications, lab environments, and defense technologies.
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![GettyImages-1480979249-consulting-office-computer-windows]( "Manufacturing Execution System Consulting Services")
We support you in the process of optimally implementing complex Manufacturing Execution Systems. In addition to the creation of Master Batch Records (MBRs) and Electronic Batch Recording (EBR), including classic data acquisition and preparation, as well as all other processes that have immediate effects on the manufacturing process.
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![Isolated Antibody Drug Conjugates ADCs GettyImages-1438509824]( "Antibody-Drug Conjugates")
Antibody drug conjugates (ADCs) are the emerging class of anti-cancer therapeutic drugs. ADCs combine an antibody capable of recognizing cancer cells and cytotoxic small-molecule drugs via cleavable or non-cleavable linkers, thereby transforming the 3-unit combination into a targeted therapeutic drug for cancer treatment. In recent years, ADCs have rapidly developed and there are not only more than 14 approved drugs on the market but also many investigational drugs undergoing clinical trials. Furthermore, ADCs have shown potential for treating various diseases beyond cancer, such as Autoimmune disorders, Infectious diseases, Inflammatory conditions and so on.
WHITE PAPERS AND CASE STUDIES
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![GettyImages-1367890497 culture]( "Optimizing Upstream Process Development To Increase mAb Titers")
Optimizing Upstream Process Development To Increase mAb TitersUncover how we were able to help a client develop an efficient upstream process for a novel monoclonal antibody (mAb), resulting in a more than 100% increase in titers.
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![Axine-electraCLEAR]( "Achieving Complete Destruction Of PFAS Using electraCLEAR Process")
Achieving Complete Destruction Of PFAS Using electraCLEAR ProcessIn early 2023, Lacks Enterprises Inc., a large automotive component supplier in the midwestern US, engaged Axine to address destruction of legacy PFAS compounds in wastewater from its manufacturing processes.
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![GettyImages-1327112218 Scientist using a laptop in a laboratory]( "Electronic Batch Reporting")
Electronic Batch ReportingLearn how a CDMO automatically created a comprehensive batch report model to drive their reporting and speed root cause identification of quality failures with an Industrial DataOps software solution.
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![GettyImages-1460849709 santa clarita CA]( "Removal Of PFAS Contamination In Water Supply: Santa Clarita, CA")
Removal Of PFAS Contamination In Water Supply: Santa Clarita, CALearn how PFAS-selective ion exchange resin offers a compact, high-efficiency alternative to traditional carbon filtration. This overview highlights the technical benefits of faster kinetics, reduced equipment footprint, and superior removal of short-chain compounds for long-term water quality compliance.
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![yorkshire-water-feature]( "Yorkshire Water Reduces Leaks By 57%, Eliminating 30% Of Annual Distribution Main Repairs")
Yorkshire Water Reduces Leaks By 57%, Eliminating 30% Of Annual Distribution Main RepairsYorkshire Water Services (YWS) is a leading UK water utility that serves nearly 5.5 million people and has a well-deserved reputation as a progressive and proactive utility. Their belief that innovation is one of the key driving forces that allows utilities to deliver better services to their customers while keeping costs down has led them to always seek out new ways to improve their operations both now and in the future.
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![easley]( "How Easley Combined Utilities Cut Sludge Handling Costs By One-Third")
How Easley Combined Utilities Cut Sludge Handling Costs By One-ThirdDiscover how a municipal wastewater treatment plant reduced its overall sludge management expenses by one-third and improved daily operational efficiency by implementing an advanced thickening system to streamline solids management and reduce hauling logistics.
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![regeneron-cgmp-gowning-cleanroom-5]( "Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements")
Mobile Gowning Cleanroom, Built To Meet ISO 7 RequirementsUncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.
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![WOL_south-dearborn_385x250]( "Resolving Odor Complaints With Targeted Solutions Restore Community Confidence")
Resolving Odor Complaints With Targeted Solutions Restore Community ConfidenceThe South Dearborn Regional Sewer District in Lawrenceburg, Indiana, provides regional wastewater treatment services for three cities and an international distillery. The 6 mgd treatment plant is located in an area of high population growth and is surrounded by many retail operations and other commercial developments. In addition, a heavily traveled state highway runs by the treatment plant.
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![GettyImages-1693748594 phone]( "Retention And Access In NSCLC Clinical Trials")
Retention And Access In NSCLC Clinical TrialsHelping participants navigate respiratory limitations, fatigue, and complex visit schedules in Non-Small Cell Lung Cancer (NSCLC) studies.
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![GettyImages-1400967286 regulations computer]( "Optimizing Early-Stage Oncology")
Optimizing Early-Stage OncologyA strategic partnership enables a U.S. biotech company to address the struggles with their Phase I first-in-human oncology trial.
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![GettyImages-525755915 clinical team eCOA]( "Improving Patient Health And Safety")
Improving Patient Health And SafetyEngage an experienced CMC program management consultant to collaboratively develop and maintain a robust product development plan (PDP) with your team lead, cross-functional members, and vendors.
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![GettyImages-974024224-molecule string-molecule cluster]( "Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes")
Leveraging Surface Plasmon Resonance For Characterizing Ternary ComplexesUncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.
NEWS
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INTECH: TRUMPF Uses AI To Improve Laser Cutting Edges3/18/2025
At its in-house INTECH trade fair, TRUMPF is showcasing its “Cutting Assistant,” an application which uses artificial intelligence to improve the quality of laser-cut edges.
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NEOVAC Presents Innovative Vacuum Coating Technology For High-Strength Steels With No Thermal Stress8/27/2025
NEOVAC, a joint venture between SMS group GmbH and SITIZN Group Holding AG, based in Karlstein, Germany, is proud to present a brand new technology for coating steel strip, which was specially developed for high-strength and ultra-high-strength steels.
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New Sensaphone Sentry Remote Monitoring System: Next-Generation Alternative To Legacy Landline Auto Dialers5/12/2025
The new Sensaphone Sentry remote monitoring system is an ideal replacement for traditional landline-based auto dialer devices that are becoming obsolete because they rely on outdated, often unsupported, copper telephone lines.
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Ideal Nitrogen Fertilizer Rates In Corn Belt Have Been Climbing For Decades, Study Shows3/3/2025
The amount of nitrogen fertilizer needed to maximize the profitability of corn production in the Midwest has been increasing by about 1.2% per year for the past three decades, according to new Iowa State University research.
ABOUT
About Nutrient Removal
Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.
As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.
The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.
Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.
Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.