RFICs

WHITE PAPERS AND CASE STUDIES

• Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches

  Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

• How ABB Is Helping Optimize Combustion At Twence's Waste-To-Energy Plant

  Maintaining the right level of oxygen is crucial for combustion optimization. Too much excess oxygen equals decreased efficiency. Read more about how ABB is helping Twence optimize combustion in their waste-to-energy plant in the Netherlands.

• Successful EU MAA Submission Enabled By U.S.–EU Regulatory Collaboration

  Facing EU MAA complexity? Learn how one oncology sponsor met a fixed EMA deadline through global regulatory coordination, rapid dossier adaptation, and real-time submission execution.

• Reservoir Service Preserved During Emergency Leak Repair

  Discover how utility operators resolved a critical emergency main leak in just one day, using under-pressure valve insertion to isolate the break without draining the regional reservoir or interrupting water service to the community.

• Innovative Water Reuse Solutions With Xylem's Advanced Treatment Technology

  Transitioning to advanced purification methods like UV-hypochlorite oxidation allows municipalities to secure reliable, local water supplies. These strategies mitigate drought risks and protect coastal environments by transforming wastewater into a high-quality resource for reuse.

• Unravelling Immunological Depths: Exploring Oxazolone-Induced Delayed-Type Hypersensitivity Model

  Validating the oxazolone-induced DTH mouse model offers a critical platform for advancing the evaluation of therapeutic candidates for chronic inflammatory diseases, including atopic dermatitis.

• Supporting A CAR T-Cell Therapy Study In Hematologic Malignancies

  To address a life-threatening complication of immunotherapy in hematologic malignancies, a U.S. biotech company developed a novel compound.

• 82 Million Gallons In. Zero PFAS Out.

  Ion exchange resin is a reliable, high-capacity solution for municipal PFAS treatment, demonstrating zero detectable PFAS after processing 82 million gallons of water. The technology offers a significantly smaller footprint and superior volumetric capacity compared to GAC. Read the full case study to review performance data and strategic impacts.

• AVT - AVT EZ Valve Install Keeps Work On Track At German Oil Refinery

  Industrial repairs at height require lightweight, efficient solutions to maintain production schedules. Under-pressure valve insertion allows for the rapid creation of isolation points on elevated pipelines, ensuring system continuity and safety without the need for extensive shutdowns.

• Designing, Developing, And Validating A Precision Extruded Tube In Just 8 Weeks

  A multinational medical device company worked to redesign an introducer sheath for a neurovascular microcatheter. After successful prototypes, the design was completed in 8 weeks.

• Groundwater DWTP (NJ) – DEXSORB Full-Scale

  Cyclopure was invited to replace ion exchange resin to remove PFAS from groundwater at a groundwater pump station, located in New Jersey. The decision to replace IXR was due to poor PFAS removal caused by manganese fouling.

• How Compassion Shaped This Pediatric Rare Disease Trial

  Learn how kindness transformed the clinical trial experience for pediatric rare disease participants in a global study.