RFICs

PRODUCTS

  • Isolated Antibody Drug Conjugates ADCs GettyImages-1438509824
    Antibody-Drug Conjugates

    Antibody drug conjugates (ADCs) are the emerging class of anti-cancer therapeutic drugs. ADCs combine an antibody capable of recognizing cancer cells and cytotoxic small-molecule drugs via cleavable or non-cleavable linkers, thereby transforming the 3-unit combination into a targeted therapeutic drug for cancer treatment. In recent years, ADCs have rapidly developed and there are not only more than 14 approved drugs on the market but also many investigational drugs undergoing clinical trials. Furthermore, ADCs have shown potential for treating various diseases beyond cancer, such as Autoimmune disorders, Infectious diseases, Inflammatory conditions and so on.  

  • GettyImages-1327977866-cell-culture-sample-laboratory
    Development Solutions For Biologics CHO CLD Platforms

    Aragen offers choice of CLD platforms, efficient Upstream and Downstream process development

  • Culture bioreactor
    Leverage Bioreactor Capacity When You Need It With Culture Bioreactors

    Gain access to Culture bioreactors when you need rapid overflow experimental capacity.

    Benefits

    Progress studies faster

    Run overflow projects and conduct parallel experiments with Culture to reduce time and alleviate bottlenecks.

    Stay agile in your capacity planning

    Scale your workload at Culture according to your current needs. Respond rapidly to surging demands.

    Eliminate your capital equipment spend

    Leverage Culture’s facility quickly to avoid building out lab space, spending capital on equipment, and hiring specialized staff.

  • Trimble Connect: Common Data Environment

    Connect the right people to the right data at the right time with Trimble Connect, a cloud-based common data environment (CDE) and collaboration platform designed specifically for the construction industry.

  • Flex-Line Feature
    Robotic Pharmaceutical Aseptic Filling System

    Fast-track your market entry with our robust aseptic filling platform. The Flex-Line™ Robotic Filler provides full integration of Scientific Products filling and Comecer isolation technologies for a seamless process from order through Validation.

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About Nutrient Removal

Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.

As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.   

The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.

Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.

Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.