RFICs
PRODUCTS
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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The Isolator Glove Testing System enables for Annex 1 compliant wireless and tubeless leak testing of gloves installed in Isolators or RABS. The GTS with the latest software technology offers an extremely flexible and fully integrable solution for glove testing as part of glove management.
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The N-332 linear stage, powered by PICMAWalk, the longest-lasting piezo-motorized drive principle on the market, delivers an impressive 75 N active force with a 3 nm minimum incremental motion.
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The MDPX-00006PSM is a versatile MMIC surface-mount diplexer designed to multiplex signals across two distinct frequency ranges: low-frequency DC to 10 GHz and high-frequency 12 to 28 GHz.
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UltraLite RF Cable Connectors are designed to perform at high frequencies and harsh environments with lower weight compared to their steel and brass counterparts by leveraging aluminum construction.
WHITE PAPERS AND CASE STUDIES
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High Drug Tolerance ADA Testing For Long‑Acting mAbs
See how advanced ADA assay design overcomes extreme drug interference, enabling reliable immunogenicity assessment for long‑acting, high‑dose monoclonal antibodies in early clinical development.
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Flexible Integrations To Reduce Risks And Increase Efficiencies
Learn how a trial team kept the blind of central lab samples and patient treatment across a Phase III and extension trial, whilst optimizing the supply chain.
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Accelerating A Complex Molecule From CLD To cGMP In 12 Months
Learn how to mitigate technical risk, implement parallel process development, and design custom purification strategies for highly sensitive novel modalities to accelerate to cGMP material.
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Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements
Uncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.
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Pasteurized Equivalent Water For AgriMark-Cabot Dairy In Vermont
Discover how AgriMark-Cabot Dairy transformed wastewater into a valuable resource using UV technology, achieving significant energy and water savings while maintaining stringent food safety standards.
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Improving Clinical Research Efficiency And Access For Underserved Populations
Modernizing data workflows removes geographic barriers to clinical trials, ensuring rural patients access innovative care while reducing administrative burdens on dedicated research staff.
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Cooling Tower Crisis: How Hydrogen Peroxide Scrubbed Away The Bacteria Buildup
A West coast power plant needed an immediate solution to clean its cooling tower that was fast, cost effective, and did not require removal and manual cleaning of the tower's fill material.
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Vaccine Fill Line Operations
Learn how adopting a harmonized, risk-based validation strategy across global sites can reduce operational readiness timelines and drive improvements in equipment effectiveness and regulatory compliance
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How Optina Diagnostics Used EDC In Earlier Disease Detection
Understand how Optina Diagnostics streamlined operations and achieved significant milestones by leveraging Castor's tools in its effort to revolutionize the diagnostic process for Alzheimer’s.
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Re-Engineering A Complex Process For FDA Compliance
Discover the strategies that helped a company navigate a complex and shifting regulatory landscape to rapidly re-engineer a COVID-19 vaccine manufacturing process for FDA compliance.
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Controlling Biofouling In Governador José Richa Power Plant, Brazil
Read about an extensive study that was carried out to evaluate the ability of the HOD UV system to control biofouling in the Governador José Richa Power Plant.
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Aquatic Invasive Species Control At Hoover Dam
In this case study, learn why Hoover Dam installed Atlantium's HOD UV treatment system to protect its cooling water systems from Quagga mussels.
NEWS
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
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Ovarro Opens New Asia Pacific Headquarters8/27/2025
Water technology provider Ovarro has opened a new Asia Pacific headquarters and production facility in Selangor, Malaysia.
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Plants Don't Just Feel The Heat – They Decode It Through A Molecular Network6/13/2025
In a new framework that could reshape how we engineer crops for a warming world, scientists have revealed that plants don't rely on a single "thermometer" to sense temperature.
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Be Part of Photonics Future: CIOE 2025 Visitor Registration Live Now!4/9/2025
The 26th China International Optoelectronic Exposition (CIOE 2025) is set to take place from September 10–12, 2025, at the Shenzhen World Exhibition & Convention Center, spanning 240,000 square meters of exhibition space.
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Redex Preloaded Systems Deliver Precise Positioning For Machine Tools1/16/2025
Redex is pleased to announce its patented DualDRIVE and TwinDRIVE preloading technologies now give CNC machine designers several ways to build a zero backlash system.
ABOUT
About Nutrient Removal
Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.
As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.
The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.
Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.
Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.