RFICs

WHITE PAPERS AND CASE STUDIES

• Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs

  By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

• Cell Line Development For High-Titer Lentivirus Vector Production

  Explore a groundbreaking method to significantly enhance LV vector yield using engineered HEK293T cells. This approach paves the way for more efficient and large-scale production of LV vectors.

• Supporting Participants Through National Travel Disruptions

  A sudden travel shutdown threatened a critical clinical visit. Rapid rescheduling, coordinated logistics, and clear communication ensured engagement and the ability to continue without interruption.

• Overcoming HCP Co-Elution Issues Using Cell Line Engineering

  Product quality assessments revealed that a customer’s therapeutic protein had a range of hydrophobic HCPs. Review a solution that took an alternative approach by utilizing cell line engineering.

• Use Of Epiontis ID In A Phase 2 Psoriasis Trial

  Mirikizumab’s Phase 2 trial explores IL-23 inhibition in psoriasis, measuring immune cell changes to assess its potential for long-term disease control and flare-up prevention.

• RTSM And Clinical Drug Dispensation

  A pharma company used Signant Health's RTSM solution in a Phase 2 schizophrenia trial to ensure drug availability, maintain study balance, prevent duplicate allocations, and manage returns and destruction of unused drugs.

• Global Start-Up For Multinational Geographic Atrophy Trial

  This partnership allowed a leading biopharmaceutical company to navigate the complexities of a Phase IIb study investigating a novel pegylated RNA adapter for geographic atrophy secondary to dry AMD.

• Pasteurized Equivalent Water For AgriMark-Cabot Dairy In Vermont

  Discover how AgriMark-Cabot Dairy transformed wastewater into a valuable resource using UV technology, achieving significant energy and water savings while maintaining stringent food safety standards.

• ICON And Medable Drive 85% eConsent Adoption In U.S. Menopause Study

  A site-focused strategy drove strong eConsent adoption in a complex women’s health study, showing how tailored training and hands-on support boost engagement and compliance.

• Accelerating Early Phase Oncology Study Development

  Explore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.

• Increasing Productivity On The Production Line With Laser Power Measurement

  Dive into how one company's adoption of reliable laser output measurement on its production lines led to increased productivity and cost-efficiency.

• Manufacturing Transfers: Delivering 140+ Precision Medical Devices Without Missing A Deadline

  Go inside a successful manufacturing transfer of over 140 Class-III silicone medical devices and on-time delivery for a top-30 OEM through expert project management and rigorous validation processes.