RFICs
PRODUCTS
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Accelerate your drug development with our comprehensive pre-formulation, formulation, and novel delivery system expertise, tailored to optimize physical form, enhance solubility, and support scale-up.
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The VSX3746 is a high-power X-band solid-state power amplifier (SSPA) that operates within the 9.0–10.0 GHz frequency range and delivers a nominal peak RF output of 1.5 kW, with a minimum of 1.2 kW.
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Immunotherapy is an evolving and promising cancer treatment that works by stimulating the immune system. More biologically relevant human primary cells are now the chosen starting material for immunotherapy development. Historically, scientists routinely used immortalized cell lines in the research and development of therapies as they offer an inexpensive and stable platform. However, they are not fully representative of what is going on in vivo.
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At Mikart, our mission is to leverage our technical expertise in pharmaceutical development and manufacturing to deliver services that meet the diverse needs of our customers.
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As the final step before treated wastewater leaves the plant, effective disinfection is extremely important to protect human health, and the maintenance of the environment. This process eliminates pathogenic organisms that cannot be removed by previous treatment steps and reduces the spread of pathogens in the natural ecosystem.
USP’s current offerings include our unrivaled in-house CFD modeling expertise that can be used to optimize the injection, mixing and feed rates of PAA to meet the disinfection requirements of a facility. Also, launching later this year, is our OaSys iCT™ is a novel control approach that optimizes disinfection performance by calculating the optimal chemical dosage that accounts for sources of treatment variability in real time. Available for use with PAA or chlorine.
WHITE PAPERS AND CASE STUDIES
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Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes
Uncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.
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Accelerating Early Phase Oncology Study Development
Explore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.
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Cell Line Development For High-Titer Lentivirus Vector Production
Explore a groundbreaking method to significantly enhance LV vector yield using engineered HEK293T cells. This approach paves the way for more efficient and large-scale production of LV vectors.
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CDMO Uses Robotic Gloveless Isolator For Advanced Therapeutics
CDMOs must innovate production architectures to meet the demands of advanced therapeutics to ensure a reliable supply and compliance. Discover how these approaches advance modern medicine and improve patient outcomes.
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Disinfection For Drinking Water Plant In Chennai, India
The Chennai Metropolitan Water Supply and Sewerage Board (CMWSSB) encountered significant challenges in treating high algae loads at its drinking water plant, which processes 1.5 million liters of water daily. The primary issue arose from the organic load in lake water, which, when treated with conventional chlorine disinfectants, resulted in harmful disinfection byproducts (DBPs).
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Responsible Reclamation – City of Abilene, Texas
To combat drought, Abilene, Texas, implemented a reuse system utilizing O3 + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.
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Yorkshire Water Reduces Leaks By 57%, Eliminating 30% Of Annual Distribution Main Repairs
Yorkshire Water Services (YWS) is a leading UK water utility that serves nearly 5.5 million people and has a well-deserved reputation as a progressive and proactive utility. Their belief that innovation is one of the key driving forces that allows utilities to deliver better services to their customers while keeping costs down has led them to always seek out new ways to improve their operations both now and in the future.
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Drinking Water Disinfection At Lunenberg, Massachusetts, USA Local Community
In this case study, read how the Lunenburg Water District improved their water disinfection system with the installation of an Atlantium RZ300-11 HOD UV system. The system effectively disinfects water, meets future demands, and eliminates chlorine taste and odor.
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Data Key In Addressing Patient Recruitment Challenges
Explore how a Phase II trial for extensive-stage and previously treated small cell lung cancer overcame recruitment challenges with a data-driven solution designed to surface protocol-matched patients.
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Automated Trial Monitoring Workflows Make A Lean Team More Efficient
A pharmaceutical therapy developer was looking to automate reports, confirmation letters, and follow-up letters. See what happened when they adopted a cloud-based solution for end-to-end trial management.
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Achieving Complete Destruction Of PFAS Using electraCLEAR Process
In early 2023, Lacks Enterprises Inc., a large automotive component supplier in the midwestern US, engaged Axine to address destruction of legacy PFAS compounds in wastewater from its manufacturing processes.
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RTSM And Clinical Drug Dispensation
A pharma company used Signant Health's RTSM solution in a Phase 2 schizophrenia trial to ensure drug availability, maintain study balance, prevent duplicate allocations, and manage returns and destruction of unused drugs.
NEWS
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U.S. Department Of Energy Announces $6.9M In Projects To Support Effective Community Waste-To-Energy Strategies For Local Transportation Needs1/7/2025
The U.S. Department of Energy's (DOE) Bioenergy Technologies Office (BETO) and Vehicle Technologies Office (VTO) announced $6.9M in funding for nine projects to support local waste-to-energy management solutions for transportation energy needs.
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Masdar And Iberdrola Announce €5.2B UK Offshore Wind Deal And Full Energization Of 476MW German Offshore Wind Farm7/10/2025
Masdar, a global clean energy leader, and Iberdrola, one of the world’s largest energy companies, have reached two major milestones with a €5.2B co-investment in the UK’s East Anglia THREE offshore wind farm – the largest offshore wind transaction of the decade – and the full energization of their 476MW Baltic Eagle project in Germany.
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University Of St. Thomas Offers No-Cost Machining And CNC Optimization Training7/18/2025
The University of St. Thomas is launching a new, no-cost training program to help manufacturing professionals, engineers, and students upskill and gain valuable insights into using computer simulations to optimize CNC machining.
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Silo Pharma Expands Intellectual Property Portfolio With Patent Application For Exclusively Licensed Alzheimer's Drug4/28/2025
Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a patent application with the U.S. Patent and Trademark Office (USPTO) focused on the neurology drug SPC-14, an intranasal compound for the treatment of Alzheimer’s disease (AD) exclusively licensed to Silo Pharma from Columbia University.
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Vodafone Reduces Its Advertising And Media Carbon Footprint By A Third1/7/2025
Vodafone has reduced the carbon footprint of its media and advertising activities by more than a third in a year across thirteen markets in total after benchmarking its media-related greenhouse gas (‘GHG') emissions and introducing global guidelines to mitigate them.
ABOUT
About Nutrient Removal
Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.
As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.
The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.
Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.
Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.