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  • Medicine-pills-tablets-GettyImages-545993684
    USP<1062> Tablet Compression Characterization

    Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.

  • Multilog-LX2
    Multilog LX2

    Multilog LX2 is a highly versatile, battery-powered cellular data logger that incorporates a convenient serial input that supports compatibility with various sensors and meters, including Modbus.

    A powerful fast logging solution, Multilog LX2 delivers effective data recording and efficient transmission.

  • TrialKit PACS
    TrialKit Picture Archiving and Communication System (PACS)

    Whether you’re conducting an oncology trial, a neurology study, or imaging-based endpoint research, TrialKit’s flexible imaging capabilities can meet your needs.

  • GettyImages-1480979249-consulting-office-computer-windows
    Manufacturing Execution System Consulting Services

    We support you in the process of optimally implementing complex Manufacturing Execution Systems. In addition to the creation of Master Batch Records (MBRs) and Electronic Batch Recording (EBR), including classic data acquisition and preparation, as well as all other processes that have immediate effects on the manufacturing process.

  • orange-county
    Disinfection

    As the final step before treated wastewater leaves the plant, effective disinfection is extremely important to protect human health, and the maintenance of the environment. This process eliminates pathogenic organisms that cannot be removed by previous treatment steps and reduces the spread of pathogens in the natural ecosystem.

    USP’s current offerings include our unrivaled in-house CFD modeling expertise that can be used to optimize the injection, mixing and feed rates of PAA to meet the disinfection requirements of a facility. Also, launching later this year, is our OaSys iCT™ is a novel control approach that optimizes disinfection performance by calculating the optimal chemical dosage that accounts for sources of treatment variability in real time. Available for use with PAA or chlorine.

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About Nutrient Removal

Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.

As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.   

The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.

Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.

Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.