RFICs
PRODUCTS
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Empower participants, clinicians, and observers. Enable convenient and accurate outcome reporting, enhancing data quality and study efficiency with electronic patient reported outcomes (ePRO) and electronic clinical outcome assessments (eCOA).
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Planning to launch a patient-centric decentralized clinical trial? Give your clinical trial patients an app that makes it easy to participate—from anywhere at any time.
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LeakZon provides a powerful and versatile platform that adapts to your water management needs. Whether you oversee a small or large operation, LeakZon scales effortlessly to accommodate your requirements. Our seamless integration with various data sources, including GIS Data, AMI, and Billing (CIS), allows for a holistic view of your water network. This comprehensive data integration empowers you to make informed decisions, optimize operations, and maximize efficiency.
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Sulfide odor control within sanitary sewers has been practiced for over 50 years, yet only recently have substantive advances been made. Where once the choice of chemical treatment was either chlorine or iron salts, safer and more environmentally benign technologies based on nitrates, hydrogen peroxide, and/or magnesium hydroxide have gained acceptance. These new alternatives, however, can increase treatment costs substantially and present limitations in themselves. Therefore, it makes sense to explore new avenues for lessening the adverse impacts of the older, cheaper mainstays, particularly iron salts (ferrous/ferric chloride or sulfate) that provide other benefits to wastewater treatment operations.
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Oral non-sterile liquid manufacturing options offer a variety of liquid and suspension dosage solutions designed specifically around palatability — progressing from formulation development through full-scale commercial production.
WHITE PAPERS AND CASE STUDIES
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ArxZyme™ Acetone Removal For AMPAC Fine Chemicals
AMPAC faced a critical challenge with acetone management. The high acetone levels in the effluent from its chemical processing operations required an effective industrial wastewater treatment solution to meet environmental regulations and ensure safe discharge.
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Electronic Batch Reporting
Learn how a CDMO automatically created a comprehensive batch report model to drive their reporting and speed root cause identification of quality failures with an Industrial DataOps software solution.
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Supporting Participants Through National Travel Disruptions
A sudden travel shutdown threatened a critical clinical visit. Rapid rescheduling, coordinated logistics, and clear communication ensured engagement and the ability to continue without interruption.
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Enhancing Treatment Capacity With miGRATE™ Technology At Verrado WRF
Due to rapid population growth in its service area, Verrado Water Reclamation Facility (WRF) in Verrado, Arizona faced a challenge. Its existing treatment capacity of 1.54 millions of gallons per day (MGD) had become insufficient to meet the rising demand and comply with both Total Suspended Solids (TSS) and Total Nitrogen (TN) permits.
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Developing A Project Management Office (PMO) At A Small Manufacturing Site
Discover how implementing a Project Management Office transformed a small manufacturing site into a high-performing, strategic asset within a global network.
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Achieving Complete Destruction Of PFAS Using electraCLEAR Process
In early 2023, Lacks Enterprises Inc., a large automotive component supplier in the midwestern US, engaged Axine to address destruction of legacy PFAS compounds in wastewater from its manufacturing processes.
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A Community-Focused Approach To Metabolic Disease Trials
Learn how innovative strategies like free health exams, community engagement, and a comprehensive patient database helped this project achieve rapid enrollment with a high level of patient diversity.
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Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs
By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.
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Pasteurized Equivalent Water For AgriMark-Cabot Dairy In Vermont
Discover how AgriMark-Cabot Dairy transformed wastewater into a valuable resource using UV technology, achieving significant energy and water savings while maintaining stringent food safety standards.
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AquaNereda Provides The Lowest Total Cost Of Ownership For 10x Capacity Increase And Nutrient Removal Limits
The Wolcott Wastewater Treatment Plant in Kansas City chose the AquaNereda technology for its capacity and cost benefits. The system improved nutrient removal and met permit requirements.
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Global Omnium: Transforming From Conventional To Smart Water
Lessons learned from building one of the largest smart meter networks in Europe.
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A Translational Mouse Model For Non-Genetic Heterotopic Ossification
Reproducing the thermal lesion/tenotomy-induced mouse model can help overcome the challenge of unpredictable heterotopic ossification localization and enable the development of targeted interventions.
NEWS
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GD Energy Products' Y-Shaped Drilling Module Now Rated For 10,000 PSI8/18/2025
GD Energy Products (GDEP), the leading total solutions provider for the frac, drilling and well servicing pumps market, has announced its patented Y-Shaped Drilling Module is now rated for operating pressures up to 10,000 psi.
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Baden-Württemberg's Largest Solar Park Now In Operation5/28/2025
EnBW has commissioned its solar park in Langenenslingen-Wilflingen (district of Biberach in the southwest of Germany).
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Silo Pharma Expands Intellectual Property Portfolio With Patent Application For Exclusively Licensed Alzheimer's Drug4/28/2025
Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a patent application with the U.S. Patent and Trademark Office (USPTO) focused on the neurology drug SPC-14, an intranasal compound for the treatment of Alzheimer’s disease (AD) exclusively licensed to Silo Pharma from Columbia University.
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
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PNE Group Receives Permits For Three New Wind Farms In Germany7/8/2025
In the second quarter of 2025, the PNE Group received the necessary permits for the construction and operation of three onshore wind farms in the German states of Brandenburg, Hesse, and North Rhine-Westphalia.
ABOUT
About Nutrient Removal
Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.
As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.
The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.
Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.
Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.