RFICs

WHITE PAPERS AND CASE STUDIES

• RTSM And Clinical Drug Dispensation

  A pharma company used Signant Health's RTSM solution in a Phase 2 schizophrenia trial to ensure drug availability, maintain study balance, prevent duplicate allocations, and manage returns and destruction of unused drugs.

• Manufacturing With A Highly Potent API For An Ophthalmic Indication

  Review this approach to the manufacture of a nano-milled suspension of loteprednol etabonate intermediate, encompassing the entire product development spectrum and repeat client engagement.

• Boosting Recruitment Strategy For Phase III Study In Ulcerative Colitis

  Learn about the successful execution of a challenging three-arm, randomized, placebo-controlled Phase 3 study in Ulcerative Colitis despite strict inclusion criteria and a limited patient pool.

• How Bend Bioscience Standardized Operations And Boosted Compliance

  Discover how Bend Bioscience replaced its outdated CMMS with RAM to achieve rapid compliance, boost efficiency across facilities, and cut operational costs by 25%.

• Changing The Clinical Feasibility Game With AI

  AI is only as good as the data it’s built upon. Our customized AI platforms are constructed on a foundation of trustworthy, carefully curated data to produce detailed, expert-driven responses.

• Merck Process Transfer And Scale-Up Of Batch Protein A

  Explore cost-saving innovations in purification using a system that achieves consistent product quality and yield while significantly reducing resin use and enhancing large-scale efficiency.

• Enhancing Water Quality For Mountaire Farms

  Mountaire Farms resolved their wastewater facility issues by replacing mechanical surface aerators with SDOX technology, saving $38 million and improving treatment.

• Whether Half-Empty Or Half Full, Krohne Helps Back River Accurately Measure Flow

  If a pipe in a wastewater treatment plant is only 50% filled, it doesn't matter whether you call a glass half full or half empty.  When it comes to measuring the liquid in that pipe, either way presents a significant problem. 

• Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs

  By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

• Navigate The Complexities Of CGTs With Regulatory And CMC Expertise

  Explore how strategic regulatory and CMC expertise helped guide a biopharmaceutical company’s regulatory and development strategy for a cell and gene therapy product.

• Accelerating A Complex Molecule From CLD To cGMP In 12 Months

  Learn how to mitigate technical risk, implement parallel process development, and design custom purification strategies for highly sensitive novel modalities to accelerate to cGMP material.

• AI Predictive Maintenance Prevents Batch Loss And Production Shutdown

  AI-powered predictive maintenance with wireless vibration sensors prevented costly batch loss and production shutdowns in pharma manufacturing by detecting and fixing equipment issues before failures occurred.