RFICs

WHITE PAPERS AND CASE STUDIES

• Reducing The Burden Of Patient Retention And Improving Continuity

  Immunology trials often place a sustained burden on participants. However, integrating Home Trial Support (HTS) into a Phase 3 immunology trial can help improve the overall study experience.

• Navigate The Complexities Of CGTs With Regulatory And CMC Expertise

  Explore how strategic regulatory and CMC expertise helped guide a biopharmaceutical company’s regulatory and development strategy for a cell and gene therapy product.

• Multiple Fill Line Delivery Experience

  Learn how a multinational pharmaceutical company successfully implemented a global strategy for insulin cartridge filling, achieving seamless regulatory approval with zero deviations.

• RTSM And Clinical Drug Dispensation

  A pharma company used Signant Health's RTSM solution in a Phase 2 schizophrenia trial to ensure drug availability, maintain study balance, prevent duplicate allocations, and manage returns and destruction of unused drugs.

• Compaction Simulation For Tablet Technology Transfer And Scale-Up

  Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.

• Developing A Project Management Office (PMO) At A Small Manufacturing Site

  Discover how implementing a Project Management Office transformed a small manufacturing site into a high-performing, strategic asset within a global network.

• Collaborative Tech: How Dunea Is Boosting Network Visibility And Resilience

  Integrating high-frequency sensor data with digital twins enhances network visibility and accelerates response times. This collaborative approach allows utilities to detect anomalies instantly, optimize maintenance, and simulate operational scenarios to ensure long-term system resilience.

• GxP Inventory Delivers Real-Time Visibility, Operational Efficiency

  Modernize your clinical supply chain to streamline global trial operations, ensure regulatory compliance, and deliver investigational therapies to patients efficiently and reliably.

• Responsible Reclamation – City of Abilene, Texas

  To combat drought, Abilene, Texas, implemented a reuse system utilizing O₃​ + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.

• Enhancing Treatment Capacity With miGRATE™ Technology At Verrado WRF

  Due to rapid population growth in its service area, Verrado Water Reclamation Facility (WRF) in Verrado, Arizona faced a challenge. Its existing treatment capacity of 1.54 millions of gallons per day (MGD) had become insufficient to meet the rising demand and comply with both Total Suspended Solids (TSS) and Total Nitrogen (TN) permits.

• Targeted Isolation Enables Contractor Work Without Residential Shutdowns

  Discover how a regional utility deployed an inline 12-inch insertion valve in just 1.5 hours, allowing contractors to isolate active construction zones without triggering broad, disruptive water shutdowns across a residential neighborhood.

• AEC PFAS Removal System Reduces PFAS Contamination In New Jersey

  This case study demonstrates the effectiveness of a new technology for removing PFAS from well water to below the EPA’s detection limits.