RFICs
PRODUCTS
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Oral non-sterile liquid manufacturing options offer a variety of liquid and suspension dosage solutions designed specifically around palatability — progressing from formulation development through full-scale commercial production.
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Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
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Visualize continuous metabolic changes in cells in real-time and adjust cell culture conditions automatically for enhanced cell quality.
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At Mikart, our mission is to leverage our technical expertise in pharmaceutical development and manufacturing to deliver services that meet the diverse needs of our customers.
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The leading GIS-centric solution for permitting, licensing and land management—designed to simplify workflows for customers and staff. Improve public services and cross-team collaboration with a digital solution that keeps pace with the changes in your community.
WHITE PAPERS AND CASE STUDIES
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Cutting Costs, Not Corners: How PRI-TECH® Transformed Biosolids Odor Control At Bergen Point WWTP
The Suffolk County Department of Public Works tested the effectiveness and cost-efficiency of PRI-TECH® in controlling odors at a wastewater treatment plant. The technology successfully treated odors and reduced operating costs.
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From Months To Hours: MMC Medical's EDC Revolution
Learn how a specialized CRO reduced study build times by 95%. Discover strategies for template reusability and flexible resource scaling to accelerate early-stage medical device validation.
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Optimizing Early-Stage Oncology
A strategic partnership enables a U.S. biotech company to address the struggles with their Phase I first-in-human oncology trial.
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Responsible Reclamation – City of Abilene, Texas
To combat drought, Abilene, Texas, implemented a reuse system utilizing O3 + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.
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Vaccine Fill Line Operations
Learn how adopting a harmonized, risk-based validation strategy across global sites can reduce operational readiness timelines and drive improvements in equipment effectiveness and regulatory compliance
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Container Closure Integrity Test Method Development For Autoinjectors
Discover an autoinjector technology that leverages laser-based headspace analysis for container closure integrity to advance biologic drug delivery with precision, safety, and regulatory confidence.
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Leveraging High-Pressure Sterile Filtration For Highly Viscous Solutions
This research demonstrates the potential of high-pressure sterile filtration to enhance efficiency, reduce waste, and accelerate the development of innovative therapies.
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RO Membrane Protection For A Desalination Plant In Mejillones, Chile
Read about a seawater desalination plant that presented with several performance issues and chose the HOD UV system to control biofouling on the RO membranes.
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CAR-T And Laminar Flow Glovebox Isolators
A request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.
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Improving Patient Health And Safety
Engage an experienced CMC program management consultant to collaboratively develop and maintain a robust product development plan (PDP) with your team lead, cross-functional members, and vendors.
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Aquatic Invasive Species Control At Gavins Point Dam
In this case study, read about how the US Army Corp of Engineers installed Hydro-Optic UV systems at Gavins Point Dam to protect turbines from invasive species. The system uses UV light to disinfect and has a TIR-based design for increased effectiveness.
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ATAD Provides Increased Capacity With No Odors
Faced with persistent odor complaints and limited space, Douglas County Sewer District #1 in East Wenatchee, Washington, turned to the ThermAer second-generation Autothermal Thermophilic Aerobic Digestion (ATAD) system to modernize its biosolids treatment.
NEWS
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Drawing Inspiration From Ancient Chemical Reactions3/20/2025
To help find solutions to the planet’s climate crisis, MIT Associate Professor Daniel Suess is looking to Earth’s ancient past.
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Quantum Biopharma Announces Signing Of An Agreement With A Global Pharmaceutical Contract Research Organization To Prepare An IND (Investigational New Drug) Application Package For Lucid-21-302 (Lucid-MS), A First-In-Class Treatment For Multiple Sclerosis5/20/2025
Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) (“Quantum BioPharma” or the “Company”), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, today announces that it has signed an agreement with a global pharmaceutical contract research organization to prepare an IND (Investigational New Drug) application package for Lucid-21-302 (Lucid-MS) with the US FDA.
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Evonik Partners With ST Pharm To Increase Its Offerings For RNA And Nucleic Acid Delivery1/8/2025
Evonik is partnering with ST Pharm, a company that manufactures active ingredients for gene therapy, to expand its RNA and nucleic acid therapeutic services.
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NX Filtration And Eau d'Azur Partner For Advanced Micropollutant Treatment In Nice8/25/2025
NX Filtration, a global leader in advanced hollow fiber membrane technology, is proud to announce its collaboration with Eau d’Azur, the public company responsible for drinking water and wastewater services for the Nice Côte d'Azur Metropole.
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Silo Pharma Expands Intellectual Property Portfolio With Patent Application For Exclusively Licensed Alzheimer's Drug4/28/2025
Silo Pharma, Inc. (Nasdaq: SILO) (“Silo” or the “Company”), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a patent application with the U.S. Patent and Trademark Office (USPTO) focused on the neurology drug SPC-14, an intranasal compound for the treatment of Alzheimer’s disease (AD) exclusively licensed to Silo Pharma from Columbia University.
ABOUT
About Nutrient Removal
Nutrient removal from wastewater consists of treating wastewater to remove nitrogen and phosphorus before it reenters natural waterways. High levels of nitrogen and phosphorus in wastewater cause eutrophication, a process where excess nutrients stimulate excessive plant growth such as algal blooms and cyanobacteria. The decomposition of the algae by bacteria uses up the oxygen in the water causing other organisms to die. This creates more organic matter for the bacteria to decompose. In addition, some algal blooms can produce toxins that contaminate drinking water supplies.
As authorized by the Clean Water Act, the National Pollutant Discharge Elimination System (NPDES) permit program regulates point sources, such as municipal wastewater treatment plants, that discharge pollutants as effluent into the waters of the United States. In recent years, many of the States’ environmental bodies have lowered nutrient limits to arrest eutrophication. Maryland’s effort to protect the Chesapeake Bay and its tidal tributaries is perhaps the most notable example of nutrient removal in the US. Nutrient removal continues to be a growing area of focus for wastewater treatment throughout the world.
The removal of nitrogen and phosphorus require different nutrient removal processes. To remove nitrogen, the nitrogen is oxidized from ammonia to become nitrate through a process called nitrification. This process is then followed by denitrification where the nitrate is reduced to nitrogen gas which is released to the atmosphere and removed from the wastewater.
Nitrification is a two-step aerobic process which typically takes place in aeration tanks. Denitrification requires anoxic conditions to encourage the appropriate biological conditions to form. The activated sludge process is often used to reduce nitrate to nitrogen gas in anoxic or denitrification tanks.
Phosphorus can be removed biologically using polyphosphate accumulating organisms (PAOs) which accumulate large quantities of phosphorus within their cells and separate it from treated water. Phosphorus removal can also be achieved by chemical removal. Once removed as sludge, phosphorus may be stored in a land fill. However, many municipalities and treatment facilities are looking to resell the biosolids for use in fertilizer.